

AlphaFold does a couple of things. It’s capability in predicting how a single protein will be folded tends to be quite nice, but organisms often rely on complex interactions between proteins. It has a feature to calculate the folding of two or more proteins with each other, which is incredibly important to understand more complex interactions in various processes in the human body, as well as drug interactions.
It is also easier to create a database of folding for all normal proteins in the human body. Any change in your DNA, which is somewhat more common than people think, can modify your proteins to one that has not been seen before, since many proteins can have chunks that don’t do anything but act as filler. Except, when those changes affect a bit that doesn’t act as filler or make the filler suddenly interact with other proteins or structures, like making the protein fold entirely differently or become hydrophobic where it shouldn’t be, then you’re in trouble.
These modified proteins need to be analyzed as well and when their primary function in your body is to interact with other proteins, then this multimer functionality is critical. And that certainly needs much more research, as it is very, very far from perfect.





The notion does feel a little cynical. It’s not like this is necessarily always the case and, even if such projects will fundamentally always be an attempt at making money in the hands of large studios, they can be well executed regardless.
It’s an example of the other way around, but as someone who frankly was immune to the notion of nostalgia from it, I recently watched the first Alien movie for the first time and played Alien Isolation afterwards. That was an amazing example of a game that really represented the ambience, notion and feel of the originals without being a carbon copy of it (even if they did rely overmuch on parallels in some parts and the general structure is surely more than inspired).
Though I suppose I must also give the point that I can’t think of an example of the game to movie pipeline that ended well. I’m sure someone will be able to share some positive experience there.